PGDLLA
Poly(glycolide-co-DL-lactide)
Poly(glycolide-co-lactide) (PGLA) is obtained by the ring-opening co-polymerization of glycolide (cyclic dimer of glycolic acid) and lactide (cyclic dimer of lactic acid) as monomers.
Since lactide has 3 optical isomer as L-lactide, D-lactide, and DL-lactide, the copolymer of glycolide and L-lactide is abbreviated to PGLA, while the copolymer of glycolide and DL-lactide is abbreviated to PGDLLA.
| Chemical name | Poly(glycolic acid-co-DL-lactic acid) Poly(glycolide-co-DL-lactide) Poly[oxy(1-oxo-2-methylethylene)-co-oxy(1-oxoethylene)] Poly[oxy(2-oxoethylene)-co-oxy(1-methyl-2-oxoethylene)] |
| Chemical formula | −(C2H2O2)n−(C3H4O2)m− −O−CO−CH2−O−CO−CH(CH3)− |
| Formula weight | 130.09874 |
| CAS number | 34346−01−5, 26780−50−7 |
| Characteristics | Soluble into general organic solvents |
Typical specification of PGDLLA
The following shows the specification example of our PGDLLA polymer (PGDLLA(25:75)) product.
| Testing item | Specification |
| Identification | Same as the standard NMR spectrum of PGDLLA. Identification |
| Composition | CGA:CLA =20:80 − 30:70 (mol%) |
| Weight averaged molecular weight(MW) | MW = 220,000 − 280,000 |
| Glass transition point（Tg） | Tg = 50 − 60 (℃) |
| Particle size | Not passing 500 µm mesh screen. |
| Appearance | No contamination by foreign objects Normal coloring (white or beige or ivory) (Sensory test with eye) |
※If you have the specific requirement for PGDLLA polymer, please feel free to ask us.
Potential application of PGDLLA
PGDLLA polymer mainly applied for GTR-membranes (porous membranes) for regeneration and adhesion of lost periodontal supporting tissues caused by periodontal disease. (GTR: Guided Tissue Regeneration)
Applicable examples of the medical device obtained from PGDLLA polymers are shown with color in follows:
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